The island seems to be abandoned, though at one point it might've been inhabited. This is indicated by the temple surrounding the entrance to the Tiger Widow's lair and the presence of several human skeletons stuck in the webs.
The Ninja explore this island to get Tiger Widow's venom. While Jay explores the Tiger Widow's cave, he's attacked by the titular beast of the island and manages to retrieve its venom. After an attack by the Sky Pirates, the Ninja send the Tiger Widow plummeting into a chasm by destroying a bridge.
As a result of Jay erasing the events of the season, little was changed to the island, save for the reconstruction of its rope bridge.